Related Papers
Rhinology
Therapeutic Index (TIX) for intranasal corticosteroids in the treatment of allergic rhinitis
2011 •
C. Bachert
Intranasal corticosteroids (INS) are the first line treatment for allergic rhinitis (AR). To guide clinical decision-making, we created a therapeutic index (TIX) for INS reflecting efficacy and safety. A Medline search (1966 to June 2009) was carried out to identify all placebo-controlled randomized trials, and observational reports for safety issues, with Dexamethasone, Budesonide (BUD), Fluticasone propionate (FP), Fluticasone furoate (FF), Flunisolide, Mometasone furoate (MF), Triamcinolone (TRIAM), and Beclomethasone dipropionate (BDP) as treatment for AR. Data on three efficacy (nasal symptoms, ocular symptoms, global assessment) and three safety outcomes (epistaxis, growth, systemic ocular effects) were extracted. Meta analyses were performed for each INS and outcome and results were categorised into scores by quartiles. Scores of the three efficacy and safety outcomes were summed up to create summation scores for efficacy (ES) and side effects (AES), respectively with a maxim...
Rhinology journal
As-needed intranasal corticosteroid spray for allergic rhinitis: a systematic review and meta-analysis
Wirach Chitsuthipakorn
Background: As-needed intranasal corticosteroid spray (INCS) is commonly used by patients with allergic rhinitis (AR) who have suboptimal symptom control. This systematic review aimed to assess the effectiveness of as-needed INCS for treating AR. Methodology: Systematic searches for randomized controlled trials studying the effects of as-needed INCS compared to regular INCS, as-needed antihistamine, or placebo were performed. Primary outcomes were total nasal symptom score (TNSS) and disease-specific quality of life (DSQoL). Results: Eight studies (882 participants) met the criteria. Regular use of INCS showed greater improvements than as-needed INCS in TNSS, DSQoL, nasal peak inspiratory flow, sneezing, and nasal congestion scores with small effect sizes. There were no differences between regular and as-needed INCS usage for ocular symptoms, symptom-free days, nasal itching, and rhinorrhea scores. As-needed INCS was superior to as-needed antihistamine and placebo with medium effect...
International Forum of Allergy & Rhinology
Effects of H1 antihistamine addition to intranasal corticosteroid for allergic rhinitis: a systematic review and meta-analysis
2018 •
Wirach Chitsuthipakorn
Cureus
Safety Concerns of Nasal Corticosteroids Usage in Patients With Allergic Rhinitis
2020 •
Fahad Alotaibi
Background Intranasal corticosteroids (INCSs) are the first-line treatment for patients with moderate to severe conditions of allergic rhinitis (AR) as per current guidelines. However, patients' knowledge and practice towards the safety of such medications remains ambiguous. Therefore, this study was undertaken to identify the awareness of and knowledge about the safety of nasal corticosteroid usage in patients with allergic rhinitis as well as their adherence to taking the medication. Materials and methods We conducted a cross-sectional study from June to September 2020 at Imam Mohammad Ibn Saud Islamic University Medical Center, Riyadh, Kingdom of Saudi Arabia. Data were collected through questionnaire-based surveys, and a total of 375 patients were enrolled in the study. The eligibility criteria included all adult patients diagnosed with allergic rhinitis. Results Most of the patients had used intranasal corticosteroids. However, only two-fifths of patients stated these medic...
The Role of Corticosteroids in Allergic Rhinitis Treatment
Murat Enöz
Annals of Allergy, Asthma & Immunology
Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis
2002 •
Anahí Yáñez
Journal of Allergy and Clinical Immunology
Corticosteroids in the treatment of pediatric allergic rhinitis
2001 •
Glenis Scadding
Journal of Evidence Based Medicine and Healthcare
A Study of Allergic Rhinitis with Special Reference to Use of Intranasal Corticosteroid in Its Treatment in a Tertiary Care Hospital
2020 •
Saumendra Nath Bandyopadhyay
BACKGROUND Allergic rhinitis is a fairly common condition. A large number of patients of allergic rhinitis are usually found in daily ENT practice. Symptoms of allergic rhinitis are still a major problem, which can affect day to day activities of an individual. Intranasal corticosteroid has potent anti-inflammatory actions and is believed to exert its beneficial effects by inhibiting several types of cells and chemicals involved in immune and inflammatory responses. Present study determines the efficacy of intra nasal corticosteroid over placebo in patients of allergic rhinitis. METHODS A single blinded non-randomised trial was conducted among patients attending allergy clinic of ENT out-patient department of a Tertiary Medical College & Hospital of West Bengal, India from March 2008 to May 2008. Two groups of patients were selected from the total sample size of 100 patients by alternate sampling technique. One group (Gr-F) was treated by intranasal corticosteroid (fluticasone nasal...
Annals of Allergy, Asthma & Immunology
Concerns about intranasal corticosteroids for over-the-counter use: position statement of the Joint Task Force for the American Academy of Allergy, Asthma and Immunology and the American College of Allergy, Asthma and Immunology
2006 •
Phil Lieberman
Allergy
Impact of intranasal corticosteroids on asthma outcomes in allergic rhinitis: a meta-analysis
2013 •
SDN LOHIA
